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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193126Generated: October 27, 2026

2-Chloro-6-methylnicotinic acid → 4-(1H-1,2,3-Triazol-1-yl)nicotinic acid

https://huagongshe.com/reaction/1193126

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylnicotinic acidHCID 121724—
Reactant4-Chloronicotinic acidHCID 818229—
Reactant6-Methyl-2-[1,2,3]triazol-2-yl-nicotinic acidHCID 67086855—
Product4-(1H-1,2,3-Triazol-1-yl)nicotinic acidHCID 67086995—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 47 substituting 4-chloronicotinic acid for 2-chloro-6-methylnicotinic acid. MS (ESI):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08680275B2
Source datasetuspto-grants-2014_03
ORD IDord-20febbc00b6e4b4eb9b6991e856c74aa
Source noteuspto-grants-2014_03