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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193207Generated: October 31, 2026

6-Chloro-N-cyclopropylpyrimidin-4-amine → HCID 67116854, compound

https://huagongshe.com/reaction/1193207

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-N-cyclopropylpyrimidin-4-amineHCID 22309479—
Reactant(1R,6S)-3,8-diazabicyclo[4.2.0]octan-3-yl(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanoneHCID 67116560—
Reactant2-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-quinoxalineHCID 67116651—
ProductHCID 67116854HCID 67116854—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 2, Step A, using (1R,6S)-3,8-diazabicyclo[4.2.0]octan-3-yl(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and 4-chloro-6-(cyclopropylamino)pyrimidine. MS (ESI) mass calcd. for C22H23FN8O, 434.5; m/z found, 435.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08680275B2
Source datasetuspto-grants-2014_03
ORD IDord-58bb2991968540058d7457f1493e052f
Source noteuspto-grants-2014_03