反应详情

TFA (10 ml) was added dropwise at 0° C. to a solution of (R)-methyl 3-(tert-butoxycarbonyl-amino)-2,3-dihydro-1H-indene-5-carboxylate (2.3 g, 7.9 mmol, 1 eq) in dichloromethane (50 ml), and stirring was carried out for 1 h at RT. Then the solvent was reduced under reduced pressure. The crude product was used in the following stage without being purified and analyzed further.

1. customwithout being purified