HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 66798574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 66805330 | HCID 66805330 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66798574 | HCID 66798574 | 94% |
Reaction Steps
tert-Butyl methyl(1-(pyridin-4-yl)pyrrolidin-3-yl)carbamate (3.028 mmol, 1 eq) was dissolved in ethanol (11 ml), and acetyl chloride (15.14 mmol, 5 eq) was added, while cooling with ice. After stirring for 16 h at RT, a solid precipitated. Ethanol was concentrated slightly, and the precipitate was filtered off, washed with diethyl ether and dried. Yield: 94%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680159B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-98f0969a04dc413f8977e58dd73fb29d |
| Source note | uspto-grants-2014_03 |