Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193399Generated: October 31, 2026

Trifluoroacetic acid → HCID 66798634, compound

https://huagongshe.com/reaction/1193399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-Butyl methyl(1-(6-methylpyrazin-2-yl)piperidin-4-yl)carbamateHCID 66799007—
SolventDichloromethaneHCID 6344—
ProductHCID 66798634HCID 66798634—

Reaction Steps

Trifluoroacetic acid (2 ml) was added at 0° C. to a solution of tert-butyl methyl(1-(6-methylpyrazin-2-yl)piperidin-4-yl)carbamate (250 mg, 0.816 mmol, 1 eq) in dichloromethane (10 ml) and the reaction mixture was stirred for 2 h at room temperature. Concentration under reduced pressure was then carried out. The crude product so obtained was used in the next stage without being purified further.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08680159B2
Source datasetuspto-grants-2014_03
ORD IDord-0760eee0cf744340aaafa3fb47cf7f95
Source noteuspto-grants-2014_03