Bromotrimethylsilane → HCID 86742782, compound

HRID 1193464Notes

Reaction equation

HRID 1193464 reaction equation
[CH2:1]([CH2:8][CH:9]([P:16]([O:20]C)(=[O:19])[O:17]C)[P:10]([O:14]C)(=[S:13])[O:11]C)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[Si](Br)(C)C>C(Cl)(Cl)Cl>[CH2:1]([CH2:8][CH:9]([P:16]([OH:20])(=[O:17])[OH:19])[P:10]([OH:14])(=[S:13])[OH:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 76113BromotrimethylsilaneHCID 86742783HCID 86742783, compound

Product 1

HCID 86742782HCID 86742782, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Tetramethyl 2-benzylthioethane-1,1-diphosphonate (2.45 g) in chloroform (5 cm3) was treated with an excess of trimethylsilyl bromide (5.1 g) at room temperature. The formation of the trimethylsilyl esters was monitored by 31P n.m.r. and was complete after 15 min.

Sources & evidence

ORD record
ord-1325b4ff41e748d9bee54fcbddd1993a
Source dataset
uspto-grants-1989_03
Patent number
US04810486

Reaction notes

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