Sulfuric Acid → HCID 21272298, compound

HRID 1193517Notes

Reaction equation

HRID 1193517 reaction equation
[C:1]1([N:7]2[CH:11]=[CH:10][C:9]([NH:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=3)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:20](OC(=O)C)(=[O:22])[CH3:21].S(=O)(=O)(O)O>O>[C:20]([O:19][C:16]1[CH:15]=[CH:14][C:13]([NH:12][C:9]2[CH:10]=[CH:11][N:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[N:8]=2)=[CH:18][CH:17]=1)(=[O:22])[CH3:21]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 7918Acetic AnhydrideHCID 21272324HCID 21272324, compound

Product 1

HCID 21272298HCID 21272298, compoundYield 85.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 4-(1-phenyl-1H-pyrazol-3-yl)aminophenol (2.0 g), acetic anhydride (4 g) and sulphuric acid (0.2 g) was heated at 100° C. on the steam bath for 15 minutes, water was added and the product was collected by filtration and dried to give the sub-title compound (2.0 g) as a brown solid.

Workup

  1. filtrationthe product was collected by filtration
  2. customdried

Sources & evidence

ORD record
ord-c7b934a42c4a48df9b962b340b27a5ae
Source dataset
uspto-grants-1989_03
Patent number
US04810719

Reaction notes

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