Triethylamine → HCID 14581314, compound

HRID 1193606Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([CH2:11][CH2:12][CH2:13][NH2:14])[CH:5]=[C:6]([F:10])[C:7]=1[O:8][CH3:9].C(N(CC)CC)C.[C:22](Cl)(Cl)=[S:23]>>[F:1][C:2]1[CH:3]=[C:4]([CH2:11][CH2:12][CH2:13][N:14]=[C:22]=[S:23])[CH:5]=[C:6]([F:10])[C:7]=1[O:8][CH3:9]

Participants

Reactant 3

HCID 8471Triethylamine

HCID 10040Thiophosgene

HCID 14581313HCID 14581313, compound

Product 1

HCID 14581314HCID 14581314, compoundYield 53%

Procedure

3-(3,5-Difluoro-4-methoxyphenyl)propylamine (0.0693 mol), triethylamine (0.152 mol) and thiophosgene (0.076 mol) were reacted substantially as described in Example 7G to obtain 8.8 g (53%) of a yellow oil.

Sources & evidence

ORD record: ord-1f3ceeac1c4e4cf3bab48c1eb08fc36c
Source dataset: uspto-grants-1989_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04810811

Reaction notes

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