HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bis(4-fluorophenyl)(piperidin-4-yl)methanol → HCID 14407116, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bis(4-fluorophenyl)(piperidin-4-yl)methanol | HCID 11208889 | — |
| Reactant | 1-(3-Chloropropoxy)-4-nitrobenzene | HCID 11844617 | — |
| Catalyst | Potassium Iodide | HCID 4875 | — |
| Product | HCID 14407116 | HCID 14407116 | 72.5% |
Reaction Steps
Following the procedure of Example 1 and using potassium iodide catalyst, a mixture of 9.1 g (0.03 mole) of [α,α-bis(p-fluorophenyl)]-4-piperidinemethanol and 6.7 g (0.03 mole) of 1-(3-chloropropoxy)-4-nitrobenzene were reacted to give 10.5 g of the title compound which was recrystallized from isopropyl ether, m.p. 93.5°-94.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04810713 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-ecebba50066e4be49c7f420698d0a3cb |
| Source note | uspto-grants-1989_03 |