Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193702Generated: October 26, 2026

Bis(4-fluorophenyl)(piperidin-4-yl)methanol → 1-[4-[3-[4-[Bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]propoxy]-2-methoxyphenyl]ethanone

https://huagongshe.com/reaction/1193702

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBis(4-fluorophenyl)(piperidin-4-yl)methanolHCID 11208889—
Reactant3-(p-Acetyl-m-methoxyphenoxy)propyl chlorideHCID 14407182—
Product1-[4-[3-[4-[Bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]propoxy]-2-methoxyphenyl]ethanoneHCID 14407140—

Reaction Steps

Following the procedure of Examples 1 and 66, [α,α-bis (p-fluorophenyl)]-4-piperidinemethanol and 3-(p-acetyl-m-methoxyphenoxy)propyl chloride are reacted to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04810713
Source datasetuspto-grants-1989_03
ORD IDord-0dffa5b5d017482bbcb26afb8277520d
Source noteuspto-grants-1989_03