HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bis(4-fluorophenyl)(piperidin-4-yl)methanol → HCID 23036249, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bis(4-fluorophenyl)(piperidin-4-yl)methanol | HCID 11208889 | — |
| Reactant | HCID 23036250 | HCID 23036250 | — |
| Catalyst | Potassium Iodide | HCID 4875 | — |
| Product | HCID 23036249 | HCID 23036249 | — |
Reaction Steps
Following the procedure of Example 2 and using potassium iodide catalyst, [α,α-bis(p-fluorophenyl)]-4-piperidinemethanol and 2-(3-chloropropoxy)-1-benzyloxybenzene are reacted to give 1-[3-(2-benzyloxyphenoxy)propyl]-α,α-bis(4-fluorophenyl)-4-piperidinemethanol which is reacted with hydrogen over palladium on carbon catalyst to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04810713 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-86ad3cd5f3ca42a3936c90f197704d51 |
| Source note | uspto-grants-1989_03 |