Sodium ethoxide → HCID 21270726, compound

HRID 1193877Notes

Reaction equation

HRID 1193877 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]([F:12])[C:9]([N:13]2[C:18](=[O:19])[CH:17]=[C:16]([C:20]([F:23])([F:22])[F:21])[N:15]=[C:14]2Cl)=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[CH3:25][CH2:26][O-:27].[Na+]>C(O)C>[CH2:26]([O:27][C:14]1[N:13]([C:9]2[C:10]([F:12])=[CH:11][C:2]([Cl:1])=[C:3]([CH:8]=2)[C:4]([O:6][CH3:7])=[O:5])[C:18](=[O:19])[CH:17]=[C:16]([C:20]([F:23])([F:22])[F:21])[N:15]=1)[CH3:25]

Participants

4

Reactant 2

HCID 2723922Sodium ethoxideHCID 21270772methyl 2-chloro-5-[2-chloro-6-oxo-4-trifluoromethyl-1(6H)-pyrimidinyl]-4-fluorobenzoate

Product 1

HCID 21270726HCID 21270726, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

using methyl 2-chloro-5-[2-chloro-6-oxo-4-trifluoromethyl-1(6H)-pyrimidinyl]-4-fluorobenzoate and sodium ethylate in ethanol there is obtained methyl 5-[2-ethoxy-6-oxo-4-trifluoromethyl -1(6H)-pyrimidinyl]-2-chloro-4-fluorobenzoate, m.p. 96°-98° C.;

Sources & evidence

ORD record
ord-f38a799eb43d4e2d9715b27210774004
Source dataset
uspto-grants-1989_03
Patent number
US04812164

Reaction notes

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