HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium ethoxide → 2-ethoxy-1-(4-chloro-2-fluoro-5-isopropoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | 2-chloro-1-(4-chloro-2-fluoro-5-isopropoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone | HCID 21270778 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-ethoxy-1-(4-chloro-2-fluoro-5-isopropoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone | HCID 21270780 | — |
Reaction Steps
using 2-chloro-1-(4-chloro-2-fluoro-5-isopropoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone and sodium ethylate in ethanol there is obtained 2-ethoxy-1-(4-chloro-2-fluoro -5-isopropoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone, m.p. 101°-103° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04812164 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-024ead023fc742a2b5584224c95a72eb |
| Source note | uspto-grants-1989_03 |