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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193907Generated: November 1, 2026

Pyridine → HCID 54432997, compound

https://huagongshe.com/reaction/1193907

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantIsobutyryl chlorideHCID 62325—
ReactantHCID 21270727HCID 21270727—
SolventDiethyl EtherHCID 3283—
ProductHCID 54432997HCID 54432997—

Reaction Steps

using 2-ethoxy-1-(4-chloro-2-fluoro-5-hydroxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone and isobutyryl chloride with pyridine in diethyl ether there is obtained {5-[2-ethoxy-6-oxo-4-trifluoromethyl-1(6H)-pyrimidinyl]-2-chloro-4-fluorophenyl} isobutyrate, 1NMR (CDCl3, 400 MHz): 7.38 ppm (d,1H), 7.13 ppm (d,1H), 6.58 ppm (s,1H), 4.50 ppm (m,2H), 2.87 ppm (m,1H), 1.35 ppm (d,3H), 1.34 ppm (d,3H), 1.31 ppm (t,3H);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04812164
Source datasetuspto-grants-1989_03
ORD IDord-99b2f1192e85441488b026e708729872
Source noteuspto-grants-1989_03