HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 54432997, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Isobutyryl chloride | HCID 62325 | — |
| Reactant | HCID 21270727 | HCID 21270727 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 54432997 | HCID 54432997 | — |
Reaction Steps
using 2-ethoxy-1-(4-chloro-2-fluoro-5-hydroxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone and isobutyryl chloride with pyridine in diethyl ether there is obtained {5-[2-ethoxy-6-oxo-4-trifluoromethyl-1(6H)-pyrimidinyl]-2-chloro-4-fluorophenyl} isobutyrate, 1NMR (CDCl3, 400 MHz): 7.38 ppm (d,1H), 7.13 ppm (d,1H), 6.58 ppm (s,1H), 4.50 ppm (m,2H), 2.87 ppm (m,1H), 1.35 ppm (d,3H), 1.34 ppm (d,3H), 1.31 ppm (t,3H);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04812164 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-99b2f1192e85441488b026e708729872 |
| Source note | uspto-grants-1989_03 |