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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1193909Generated: October 31, 2026

Methyl iodide → HCID 21270788, compound

https://huagongshe.com/reaction/1193909

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
ReactantHCID 21270719HCID 21270719—
SolventDimethylformamideHCID 6228—
ProductHCID 21270788HCID 21270788—

Reaction Steps

using 1-(4-bromo-2-fluoro-5-hydroxyphenyl)-2-methoxy-4-trifluoromethyl-6(1H)-pyrimidinone and methyl iodide with sodium hydride in dimethylformamide there is obtained 1-(4-bromo-2-fluoro-5-methoxyphenyl)-2-methoxy-4-trifluoromethyl-6(1H)-pyrimidinone, m.p. 175°-177° C.;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04812164
Source datasetuspto-grants-1989_03
ORD IDord-cec2200ce3f24a73b05f779ecd8da850
Source noteuspto-grants-1989_03