HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 21270736, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-ethoxy-1-(4-bromo-2-fluoro-5-hydroxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone | HCID 21270747 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21270736 | HCID 21270736 | — |
Reaction Steps
using 2-ethoxy-1-(4-bromo-2-fluoro-5-hydroxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone and methyl iodide with sodium hydride in dimethylformamide there is obtained 2-ethoxy-1-(4-bromo-2-fluoro-5-methoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone, m.p. 126°-128° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04812164 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-f65cf0ad08bf4f7d93833c34e18016bf |
| Source note | uspto-grants-1989_03 |