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HRID1193917

反应详情

EQUATION

反应方程式

HRID 1193917 的结构方程式

REACTANTS

反应物

3
结构：CI
HCID6328

Methyl iodide

CH3I

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CCOc1nc(C(F)(F)F)cc(=O)n1-c1cc(O)c(Br)cc1F
HCID21270747

未命名化合物

PRODUCTS

生成物

1
结构：CCOc1nc(C(F)(F)F)cc(=O)n1-c1cc(OC)c(Br)cc1F
HCID21270736

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

using 2-ethoxy-1-(4-bromo-2-fluoro-5-hydroxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone and methyl iodide with sodium hydride in dimethylformamide there is obtained 2-ethoxy-1-(4-bromo-2-fluoro-5-methoxyphenyl)-4-trifluoromethyl-6(1H)-pyrimidinone, m.p. 126°-128° C.