Sulfuric Acid → HCID 21270789, compound

Participants

Reaction Steps

using 1-(4-chloro-2-fluoro-5-isopropoxyphenyl)-5-fluoro-2-methoxy-4-pentafluoroethyl-6(1H)-pyrimidinone with concentrated sulphuric acid during 2 minutes at 0° C. there is obtained 1-(4-chloro-2-fluoro-5-hydroxyphenyl)-5-fluoro-2-methoxy-4-pentafluoroethyl-6(1H)-pyrimidinone, 1H-NMR (CDCl3, 60 MHz): 7.28 ppm (d,1H), 6.83 ppm (d,1H), 5.10 ppm (s,1H), 4.00 ppm (s,3H);

Provenance & Evidence