Phosphorus oxychloride → HCID 21270698, compound

Participants

Reaction Steps

using isopropyl 2-chloro-5-[3,6-dihydro-2,6-dioxo-4-pentafluoroethyl-1(2H)-pyrimidinyl]-4-fluorobenzoate with phosphorus oxychloride and pyridine within 1 hour at room temperature there is obtained isopropyl 2-chloro-5-[2-chloro-6-oxo-4-pentafluoroethyl-1(6H)-pyrimidinyl]4-fluorobenzoate, 1H-NMR (CDCl3, 60 MHz): 7.90 ppm (d,1H), 7.48 ppm (d,1H), 6.96 ppm (s,1H), 5.30 ppm (m,1H), 1.40 ppm (d,6H);

Provenance & Evidence