Bicarbonate Ion → Benzyl 4-{4-[2-(2,5-difluorophenoxy)ethoxymethyl]phenyl}-3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]piperidine-1-carboxylate
Reaction equation
[CH3:61][N:62]([CH3:63])[CH:64]=[O:65].[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH:10]([O:25][CH2:26][c:27]3[cH:28][cH:29][c:30]4[c:31]([cH:41]3)[N:32]([CH2:36][CH2:37][CH2:38][O:39][CH3:40])[CH2:33][CH2:34][O:35]4)[CH2:11][N:12]([C:15](=[O:16])[O:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:13][CH2:14]2)[cH:7][cH:8]1.[F:42][c:43]1[c:44]([O:45][CH2:46][CH2:47][OH:48])[cH:49][c:50]([F:53])[cH:51][cH:52]1.[H-:54].[Na+:55].[Na+:56].[OH:57][C:58](=[O:59])[O-:60]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH:10]([O:25][CH2:26][c:27]3[cH:28][cH:29][c:30]4[c:31]([cH:41]3)[N:32]([CH2:36][CH2:37][CH2:38][O:39][CH3:40])[CH2:33][CH2:34][O:35]4)[CH2:11][N:12]([C:15](=[O:16])[O:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:13][CH2:14]2)[cH:7][cH:8]1)[O:48][CH2:47][CH2:46][O:45][c:44]1[c:43]([F:42])[cH:52][cH:51][c:50]([F:53])[cH:49]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2fee6e0af1294b9d932416770e3cf2f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…