Nitric Acid → HCID 178509427, compound

HRID 1193967Notes

Reaction equation

HRID 1193967 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[C:8]([OH:13])[C:7]([OH:14])=[N:6]2)#[N:2].[N+:15]([O-])([OH:17])=[O:16]>>[C:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[N+:15]([O-:17])=[O:16])[N:9]=[C:8]([OH:13])[C:7]([OH:14])=[N:6]2)#[N:2]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 178509503HCID 178509503, compound

Product 1

HCID 178509427HCID 178509427, compoundYield 75%

Conditions

Temperature
25 °C

Procedure

1 g 6-Cyano-2,3-dihydroxyquinoxaline is added gradually to 10 ml of ice-cooled fuming nitric acid. The mixture is stirred at 25° C. for 1 h. The reaction mixture is poured into ice-water giving 1 g of a crude product. Recrystallization (DMF-water) gives 0.9 g (75%) of 6-cyano-2,3-dihydroxy-7-nitroquinoxaline, m.p. >300° C. IR: peak at 2240 cm-1,

Workup

  1. customRecrystallization (DMF-water)

Sources & evidence

ORD record
ord-3c0cc096c9464ac88cbbc7540b25adac
Source dataset
uspto-grants-1989_03
Patent number
US04812458

Reaction notes

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