Methyl iodide → HCID 86742804, compound

Participants

Reaction Steps

A solution of 4.2 parts of methyl trans-1-(2,3-dihydro-2-methyl-4H-1-benzopyran-4-yl)-1H-imidazole-5-carboxylate and 12 parts of iodomethane in 65 parts of dichloromethane is stirred for 20 hours at room temperature. The reaction mixture is evaporated and the residue is crystallized twice from 2,2'-oxybispropane. The product is filtered off and dried, yielding trans-1-(2,3-dihydro-2-methyl-4H-1-benzopyran-4-yl)-5-(methoxycarbonyl)-3-methyl-1H-imidazolium iodide (compound 7.04).

Provenance & Evidence