Sodium Hydroxide → HCID 14458448, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 0.4 g (0.010 mole) of sodium hydroxide in 15 ml of water and 10 ml of ethanol was added 1.2 g (0.0048 mole) of 6-ethoxycarbonyl-1,4-dioxa-7,9-dithiaspiro[4.5]decane. The reaction mixture was stirred at 60° C. for six hours. After distilling off the ethanol, the mixture was cooled in an ice/water bath. The solution was acidified with concentrated hydrochloric acid, causing a white solid to precipitate. The solid was collected by filtration, washed with water, and dried in a vacuum dessicator, yielding 1.0 g of 1,4-dioxa-7,9-dithiaspiro[4.5]decane-6-carboxylic acid as a whitish solid, m.p. 195°-197° C.

Provenance & Evidence