5-Bromo-2,4-dichloropyrimidine → HCID 14256954, compound

Participants

Reaction Steps

In 100 ml of formid acid, a reaction of 23.0 g of 5-bromo-2,4-dichloropyrimidine and 10.0 g of potassium thiocyanate was conducted at room temperature (20° C.) for 4 hours in a similar manner as Synthesis Example 1. Then, the reaction mixture was treated in a similar procedure as Synthesis Example 1, there was obtained a 80.0% yield of 5-bromo-2-chloro-4-thiocyanopyrimidine, m.p. 166.5°-170° C.

Provenance & Evidence