HCID 54517743, compound → HCID 178419538, compound

HRID 1194323Notes

Reaction equation

HRID 1194323 reaction equation
[CH2:1]([N:7]([CH3:19])[C:8]([C:10]1[O:11][C:12]([C:15](=O)[CH2:16][Br:17])=[CH:13][CH:14]=1)=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[C:20]([NH:23][C:24]([NH2:26])=[S:25])(=[NH:22])[NH2:21]>CC(C)=O>[BrH:17].[NH:23]([C:24]1[S:25][CH:16]=[C:15]([C:12]2[O:11][C:10]([C:8](=[O:9])[N:7]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[CH3:19])=[CH:14][CH:13]=2)[N:26]=1)[C:20]([NH2:22])=[NH:21]

Participants

4

Reactant 2

HCID 54517743HCID 54517743, compoundHCID 178513045HCID 178513045, compound

Product 1

HCID 178419538HCID 178419538, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 6.8 g. (0.02 mole) of N-n-hexyl-N- methyl-5-(2-bromoacetyl)furan-2-carboxamide, 2.4 g. (0.02 mole) of guanylthiourea and 225 ml. of acetone was stirred at room temperature for 2 hours. The solid was recovered by filtration (5.4 g.) and recrystallized from ethanol to give 812 mg. of the title compound as a white solid, mp. 226°-228° C.

Workup

  1. additionA mixture of 6.8 g
  2. filtrationThe solid was recovered by filtration (5.4 g.)
  3. customrecrystallized from ethanol
  4. customto give 812 mg

Sources & evidence

ORD record
ord-bfaa9fd4d65c40e69266c4ba3349810a
Source dataset
uspto-grants-1989_03
Patent number
US04814341

Reaction notes

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