1-Chloro-2-(diethylamine)ethane hydrochloride → HCID 21269535, compound

HRID 1194327Notes

Reaction equation

HRID 1194327 reaction equation
[CH2:1]([C:8]1[CH:17]=[CH:16][C:11]2[NH:12][C:13](=[S:15])[NH:14][C:10]=2[CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:18].[CH2:19]([N:21]([CH2:25][CH3:26])[CH2:22][CH2:23][Cl:24])[CH3:20].C(=O)([O-])O.[Na+]>C(O)C>[ClH:24].[ClH:18].[CH2:19]([N:21]([CH2:25][CH3:26])[CH2:22][CH2:23][S:15][C:13]1[NH:14][C:10]2[CH:9]=[C:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH:17]=[CH:16][C:11]=2[N:12]=1)[CH3:20]

Participants

5

Reactant 3

HCID 133631-Chloro-2-(diethylamine)ethane hydrochlorideHCID 516892Sodium BicarbonateHCID 21269540HCID 21269540, compound

Product 1

HCID 21269535HCID 21269535, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

6 g (25 mmoles) of 5-benzyl-benzimidazoline-2-thione, 5.16 g (30 mmoles) of 2-(diethylamino)-ethylchloride hydrochloride and 2.55 g of sodium hydrogen-carbonate are reacted in 40 ml of ethanol. After filtering off the inorganic salt and concentration of the solution, the title product is precipitated by hydrochloric ethanol.

Workup

  1. filtrationAfter filtering off the inorganic salt and concentration of the solution
  2. customthe title product is precipitated by hydrochloric ethanol

Sources & evidence

ORD record
ord-95a36fc61f684936a83627a0082e9786
Source dataset
uspto-grants-1989_03
Patent number
US04814329

Reaction notes

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