1-(triphenylmethyl)-1H-imidazole-4-carbaldehyde → HCID 14520345, compound

HRID 1194375Notes

Reaction equation

HRID 1194375 reaction equation
Br[C:2]1[CH:13]=[CH:12][C:5]2[O:6][C:7]([CH3:11])([CH3:10])[O:8][CH2:9][C:4]=2[CH:3]=1.[C:14]1([C:20]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[N:21]2[CH:25]=[C:24]([CH:26]=[O:27])[N:23]=[CH:22]2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:10][C:7]1([CH3:11])[O:6][C:5]2[CH:12]=[CH:13][C:2]([CH:26]([C:24]3[N:23]=[CH:22][N:21]([C:20]([C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=4)([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=4)[C:34]4[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=4)[CH:25]=3)[OH:27])=[CH:3][C:4]=2[CH2:9][O:8]1

Participants

3

Reactant 2

HCID 6182331-(triphenylmethyl)-1H-imidazole-4-carbaldehydeHCID 145203386-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine

Product 1

HCID 14520345HCID 14520345, compoundYield 54.5%

Procedure

Starting from 6-bromo-2,2-dimethyl-4H-1,3-benzodioxin and 1-triphenylmethyl-1H-imidazole-4-carboxaldehyde. The temperature of the reaction mixture does not exceed 40° C. Yield: 54.5% of theory; M.P.: 155°-162° C. (recrystallized from acetonitrile).

Workup

  1. customdoes not exceed 40° C
  2. customM.P.: 155°-162° C. (recrystallized from acetonitrile)

Sources & evidence

ORD record
ord-b1c06d966bc340c48388bad6b1527a8a
Source dataset
uspto-grants-1989_03
Patent number
US04814343

Reaction notes

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