HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 54724109, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 13136011 | HCID 13136011 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54724109 | HCID 54724109 | 82% |
Reaction Steps
2.1 g of 2-[3-(N,N-diethylamino)propylaminocarbonyl]-3-methoxy-1-phenylindole hydrochloride are dissolved in 5 ml of methanol and mixed with 2.5 ml concentrated hydrochloric acid. The reaction mixture is boiled for 3 h under reflux and subsequently evaporated under vacuum. 1.66 g (82% of theoretical) 2-[3-(N,N-diethylamino)propylaminocarbonyl]-3-hydroxy-1-phenylindole hydrochloride are obtained as an oily substance. IR: 1647 cm-1 (CO amide).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04814345 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-56f683bd7dac4d0598c74444208735b8 |
| Source note | uspto-grants-1989_03 |