HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanoacetamide → HCID 13772058, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanoacetamide | HCID 7898 | — |
| Reactant | 4-Acetylisoquinolin-1(2H)-one | HCID 13120164 | — |
| Reactant | HCID 53904154 | HCID 53904154 | — |
| Product | HCID 13772058 | HCID 13772058 | — |
Reaction Steps
Conventionally, these 4-acetyl isoquinolinone compounds have been prepared by condensing 2-acetyl-4-pyridyl cyclohexanone with cyanoacetamide to produce 4-cyano-1-methyl-7-pyridyl-5,6,7,8-tetrahydro-3(2H)-isoquinolinone and then reacting the obtained compound with a Grignard reagent such as methyl magnesium iodide and the like followed by decomposition by an acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04814458 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-3226e4351414445cac0439f8100cc877 |
| Source note | uspto-grants-1989_03 |