HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 19817494, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(Piperidin-1-yl)butanoic acid hydrochloride | HCID 13172081 | — |
| Product | HCID 19817494 | HCID 19817494 | — |
Reaction Steps
4-Piperidinobutyric acid hydrochloride (750 mg) and 4 ml of thionyl chloride were combined and stirred at reflux for 45 min., concentrated, triturated with ether and dried to give 700 mg of light brown solid which when dissolved in dry methanol gave Rf 0.1 in system D, distinctly different from the starting acid and presumably the methyl ester. The solid was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04814342 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-45d64b97c4ee4d46ad32035e9aa75c02 |
| Source note | uspto-grants-1989_03 |