HCID 54131587, compound → HCID 21249120, compound

HRID 1194665Notes

Reaction equation

HRID 1194665 reaction equation
[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13](=[O:20])[C:14]([CH3:19])=[CH:15][C:16]([OH:18])=[O:17]>O.C(O)(=O)C.[Zn]>[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13](=[O:20])[CH:14]([CH3:19])[CH2:15][C:16]([OH:18])=[O:17]

Participants

5

Reactant 1

HCID 54131587HCID 54131587, compound

Product 1

HCID 21249120HCID 21249120, compound

Reagents, catalysts & solvents 3

HCID 23994ZincCatalystHCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

27.3 g (0.1 mole) of the compound obtained in Example 1 are dissolved in 200 ml of water and 15 ml of acetic acid. After addition of 15 g (0.23 mole) of zinc dust, the mixture is heated under reflux for 30 minutes and filtered. The aqueous phase is rendered alkaline and extracted, the extract is acidified and the resulting oil is separated off.

Workup

  1. temperaturethe mixture is heated
  2. temperatureunder reflux for 30 minutes
  3. filtrationfiltered
  4. extractionextracted
  5. customthe resulting oil is separated off

Sources & evidence

ORD record
ord-6f14db80a4de49f681bc80b8c9e44aef
Source dataset
uspto-grants-1989_03
Patent number
US04816454

Reaction notes

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