Hydrazine hydrate (1:1) → HCID 13592809, compound

HRID 1194667Notes

Reaction equation

HRID 1194667 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12](=O)[CH2:13][CH2:14][C:15]([OH:17])=O)=[CH:8][CH:7]=1.O.[NH2:20][NH2:21]>C(O)C>[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH2:13][CH2:14][C:15](=[O:17])[NH:20][N:21]=2)=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21249155HCID 21249155, compound

Product 1

HCID 13592809HCID 13592809, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

6 g (0.024 mole) of 4-(4-(2-methoxy-ethoxy)-phenyl)-4-oxo-butyric acid and 1.2 g (0.024 mole) of hydrazine hydrate are stirred in 90 ml of ethanol at 50° C. for 1 hour. After the mixture has been cooled, the product is filtered off with suction, washed with ethanol and dried.

Workup

  1. temperatureAfter the mixture has been cooled
  2. filtrationthe product is filtered off with suction
  3. washwashed with ethanol
  4. customdried

Sources & evidence

ORD record
ord-bf70245b050948a5a99d84dd52f5495c
Source dataset
uspto-grants-1989_03
Patent number
US04816454

Reaction notes

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