HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 70352844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 70392765 | HCID 70392765 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 70352844 | HCID 70352844 | — |
Reaction Steps
7.2 g (0.02 mole) of 4-(4-(2-(2-oxo-pyrrolidin-1-yl)ethyl)-amino-carbonyl-amino-phenyl)-4-oxo-3-methyl-butyric acid and 1 ml (0.02 mole) of hydrazine hydrate are heated under reflux in 80 ml of ethanol and 10 ml of dimethylformamide for 2 hours. The crude product (6.3 g) which precipitates out on cooling is filtered off with suction and recrystallised from 90% strength ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04816454 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-3e334eec815844678aa096b9c01dd809 |
| Source note | uspto-grants-1989_03 |