Ici 109,081 → HCID 13749451, compound

Participants

Reaction Steps

5.3 g (0.03 mole) of 5-oxo-perhydro-(1,4)-thiazepine-3-carboxylic acid and 6.1 g (0.03 mole) of N,N'-carbonyl-diimidazole are stirred in 15 ml of dimethylformamide at 50° c. for 15 minutes. After addition of 4.9 g (0.03 mole) of 6-(4-amino-phenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone, the mixture is stirred at room temperature for 12 hours and the product is filtered off with suction and dried.

Provenance & Evidence