Phenol → HCID 15631970, compound

HRID 1194693Notes

Reaction equation

HRID 1194693 reaction equation
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]2=[N:6][C:7]3[CH2:8][CH2:9][N:10]([CH3:15])[CH2:11][C:12]=3[C:13](Cl)=[C:4]2[CH:3]=1.[C:18]1([OH:24])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[Cl:1][C:2]1[CH:17]=[CH:16][C:5]2=[N:6][C:7]3[CH2:8][CH2:9][N:10]([CH3:15])[CH2:11][C:12]=3[C:13]([O:24][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[C:4]2[CH:3]=1

Participants

3

Reactant 2

HCID 996PhenolHCID 12273863HCID 12273863, compound

Product 1

HCID 15631970HCID 15631970, compound

Procedure

A mixture of the compound of Example 6 (5.0 g, 0.018 mol) and phenol (3.38 g, 0.036 mol) is reacted as described for Example 14 to obtain the free base which is recrystallized three times from hexane to afford the title compound as a crystalline solid, m.p. 182°-184° C.

Workup

  1. customis reacted
  2. customto obtain the free base which
  3. customis recrystallized three times from hexane

Sources & evidence

ORD record
ord-e70e45a11e9b4837893c32da822881c3
Source dataset
uspto-grants-1989_03
Patent number
US04816464

Reaction notes

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