反应详情

A solution of 5-trifluoromethyl-m-xylene (3.4 g) and dibenzoyl peroxide (0.25 g) in 100 ml of benzene at reflux is treated with N-bromosuccinimide (4.4 g) in portions. The mixture is heated until a negative potassium iodide test is obtained. The reaction mixture is cooled and concentrated in vacuo. The residue is triturated with n-hexane and the solids are removed by filtration. The filtrate is evaporated to give the oily crude benzyl bromide.

1. customis obtained
2. temperatureThe reaction mixture is cooled
3. concentrationconcentrated in vacuo
4. customThe residue is triturated with n-hexane
5. customthe solids are removed by filtration
6. customThe filtrate is evaporated