HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → 3-Methyl-5-(trifluoromethyl)benzyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1,3-Dimethyl-5-(trifluoromethyl)benzene | HCID 20434609 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 3-Methyl-5-(trifluoromethyl)benzyl bromide | HCID 2775623 | — |
Reaction Steps
A solution of 5-trifluoromethyl-m-xylene (3.4 g) and dibenzoyl peroxide (0.25 g) in 100 ml of benzene at reflux is treated with N-bromosuccinimide (4.4 g) in portions. The mixture is heated until a negative potassium iodide test is obtained. The reaction mixture is cooled and concentrated in vacuo. The residue is triturated with n-hexane and the solids are removed by filtration. The filtrate is evaporated to give the oily crude benzyl bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04816469 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-24479168aa5c4be7b4c607b33aa822aa |
| Source note | uspto-grants-1989_03 |