Hydrochloric Acid → HCID 21268483, compound

HRID 1194764Notes

Reaction equation

HRID 1194764 reaction equation
[N:1]([O-])=O.[Na+].[NH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][S:13]([NH:16][CH2:17][CH3:18])(=[O:15])=[O:14])=[CH:8][CH:7]=1.[ClH:19]>O>[ClH:19].[CH2:17]([NH:16][S:13]([CH2:12][C:9]1[CH:10]=[CH:11][C:6]([NH:5][NH2:1])=[CH:7][CH:8]=1)(=[O:15])=[O:14])[CH3:18]

Participants

5

Reactant 3

HCID 313Hydrochloric Acid2×HCID 13286115HCID 13286115, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 21268483HCID 21268483, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Sodium nitrite (1.01) in water (12 ml) was slowly added to a stirred suspension at -5° of the finely ground product of stage (a) (3.14 g) in concentrated hydrochloric acid (30 ml) keeping the temperature below 0°. The resulting mixture was stirred at -5° for 15 min. the slowly added to a cold (-5°) stirred solution of stannous chloride (16.52 g) in concentrated hydrochloric acid (30 ml) keeping the solution below 0°.

Workup

  1. customthe temperature below 0°
  2. additionslowly added to a cold (-5°)
  3. customthe solution below 0°

Sources & evidence

ORD record
ord-66909e05d9af4985a95f920bb3f6588c
Source dataset
uspto-grants-1989_03
Patent number
US04816470

Reaction notes

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