HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 70413842, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | HCID 21268836 | HCID 21268836 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 70413842 | HCID 70413842 | — |
Reaction Steps
A mixture of 2,5 g of N-propyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-5-amine hydrochloride, 7.5 g of sodium carbonate, 11 ml of n-butyl iodide 25 ml of toluene and 25 ml of water is refluxed for 3 days. Removal of solvent from the organic layer affords an oil which is treated with ethanolic hydrochloric acid to afford N-butyl- N-propyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-5-amine hydrochloride, m.p. 161°-164°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04816474 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-625150c96fd540e6a7bf908f01f6ff5f |
| Source note | uspto-grants-1989_03 |