Hydrochloric Acid → HCID 13669829, compound

HRID 1194841Notes

Reaction equation

HRID 1194841 reaction equation
[Cl:1][C:2]1[C:15]2[O:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:16])[C:6]=2[CH:5]=[CH:4][C:3]=1[O:17][CH2:18][C:19]([O:21]CC)=[O:20].[OH-].[Na+].Cl>O>[Cl:1][C:2]1[C:15]2[O:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:16])[C:6]=2[CH:5]=[CH:4][C:3]=1[O:17][CH2:18][C:19]([OH:21])=[O:20]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 13851149HCID 13851149, compound

Product 1

HCID 13669829HCID 13669829, compoundYield 84.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of this ester (0.9 g), sodium hydroxide (0.7 g) and water (40 ml) was refluxed for 1 hour. After cooling, the mixture was rendered acidic with hydrochloric acid and the solid crystal was recovered by filtration, washed with water and dried. Recrystallization from ethanol gave 0.7 g of 4-chloro-9-oxo-9H-xanthene-3-yloxyacetic acid. m.p. 280°-281° C.

Workup

  1. temperaturewas refluxed for 1 hour
  2. temperatureAfter cooling
  3. filtrationthe solid crystal was recovered by filtration
  4. washwashed with water
  5. customdried
  6. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-a1a33d4456b54d71b53443487db8fa89
Source dataset
uspto-grants-1989_03
Patent number
US04816479

Reaction notes

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