Hydrogen Bromide → HCID 14864988, compound

HRID 1194874Notes

Reaction equation

HRID 1194874 reaction equation
[Br:1]Br.[CH:3]1([O:9]/[N:10]=[C:11](/[C:17](=[O:19])[CH3:18])\[C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1.Br>C(Cl)(Cl)(Cl)Cl.C(O)(=O)C>[CH2:15]([O:14][C:12](=[O:13])/[C:11](=[N:10]\[O:9][CH:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1)/[C:17](=[O:19])[CH2:18][Br:1])[CH3:16]

Participants

6

Reactant 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 14864954HCID 14864954, compound

Product 1

HCID 14864988HCID 14864988, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 5943Carbon TetrachlorideSolvent2×

Procedure

A solution of bromine (4.5 ml) in carbon tetrachloride (50 ml) was added dropwise to a mixture of ethyl (Z)-2-(cyclohexyloxyimino)-3-oxobutyrate (20.0 g), hydrogen bromide in acetic acid (45%, 1.0 ml) and carbon tetrachloride (150 ml) over 1.5 h, at room temperature. The mixture was stirred for 2 h, then the solvent removed in vacuo.

Workup

  1. customthe solvent removed in vacuo

Sources & evidence

ORD record
ord-7c99ca8000944d768bad4ff96b4399b4
Source dataset
uspto-grants-1989_03
Patent number
US04816452

Reaction notes

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