Bromocycloheptane → ethyl (2Z)-2-cycloheptyloxyimino-3-oxobutanoate

Participants

Reaction Steps

Ethyl (Z)-2-(hydroxyimino)-3-oxobutyrate (5.Og) was treated with cycloheptyl bromide as described in Example 13a to give the title compound as a colourless liquid (6.36 g, 80%). (Found: M+ +H, 256.1547, C13H21NO4 requires M+H 256.1550), νmax (film) 2940, 1750, 1690 cm-1 ; δH (CDCl3): 1.31 (3H, t) 1.4-2.0 (12H, m), 2.35 (3H, s) 4.32 (3H, q+m).

Provenance & Evidence