Tetrahydro-4H-pyran-4-ol → HCID 140352858, compound

HRID 1194889Notes

Reaction equation

HRID 1194889 reaction equation
[OH:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5].[O:12]1[CH2:17][CH2:16][CH:15](O)[CH2:14][CH2:13]1>>[O:12]1[CH2:17][CH2:16][CH:15]([O:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 74956Tetrahydro-4H-pyran-4-olHCID 178472876HCID 178472876, compound

Product 1

HCID 140352858HCID 140352858, compoundYield 37%

Procedure

Ethyl (Z)-2-(hydroxyimino)-3-oxobutyrate (3.0 g) was reacted with tetrahydro-4H-pyran-4-ol as described in Example 4a, Method 3, to give the title compound as a colourless liquid (1.69 g, 37%). νmax (film) 2950, 1740, 1695 cm-1. δH (CDCl3) 1.34 (3H, t), 1.82 (2H, m), 2.03 (2H, m), 2.40 (3H, s), 3.57 (2H, m), 3.91 (2H, m), 4.37 (2H, q), 4.54 (1H, m).

Sources & evidence

ORD record
ord-db0c51d4eeff46b382cc58d773906ad0
Source dataset
uspto-grants-1989_03
Patent number
US04816452

Reaction notes

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