Chloroacetonitrile → HCID 88662945, compound

Participants

Reaction Steps

Diphenylmethyl (Z)-2-hydroxyimino-2-(2-tritylaminothiazol-4-yl)acetate (1.5 g) was alkylated with chloroacetonitrile (0.38 g) as described in Example 5a to give the title compound as a white solid (1.23 g); νmax (CH2Cl2) 3400, 1740, 1535 and 1490 cm-1 ; δH (CDCl3) 4.82 (2H, s), 6.45 (1H, s), 6.98 (1H, broad s), 7.17 (1H, s) and 7.26-7.52 (25H, m). [Mass spectrum: +ve ion (3NOBA) MH+ (635) and (3NOBA/Na+) MNa+ (657)]

Provenance & Evidence