Water → HCID 13589046, compound

Participants

Reaction Steps

Diphenylmethyl (Z)-2-cyanomethoxyimino-2-(2-tritylaminothiazol-4-yl)acetate (lg) was dissolved in formic acid (98%, 40 ml) and water (10 ml) at room temperature and stirred for 12 h. The solvent was removed in vacuo and the residue triturated with ether to give the title compound as an off-white solid (0.39 g). The product was sufficiently pure for the next step; νmax (nujol) 3700-2500, 1605 (broad), 1465 and 1380 cm-1 ; δH inter alia 5.09 (2H, s), 7.04 (1H, s). [Mass spectrum: EI M+ (226)].

Provenance & Evidence