cis-2-Methylcyclohexanol → HCID 140352839, compound

HRID 1194896Notes

Reaction equation

HRID 1194896 reaction equation
[OH:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5].[CH3:12][C@H:13]1[CH2:18][CH2:17][CH2:16][CH2:15][C@H:14]1O>>[CH3:12][C@@H:13]1[CH2:18][CH2:17][CH2:16][CH2:15][C@H:14]1[O:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5]

Participants

3

Reactant 2

HCID 24006cis-2-MethylcyclohexanolHCID 178472876HCID 178472876, compound

Product 1

HCID 140352839HCID 140352839, compound

Procedure

Ethvl (Z)-2-hydroxyimino-3-oxobutyrate (1.59 g) was alkylated with cis-2-methylcyclohexan-1-ol (1.71 g) as described in Example 4, method 3. The pure title compound was otained as a pale yellow oil (0.506 g). (Found: M+, 256.1552. C13H21NO4 requires M 256.1549); νmax (film) 1745, 1695 and 1595 cm-1 ; δH (CDCl3) 1.02 (3H, d, J 6 Hz), 1.35 (3H, t, J 7 Hz), ca 1.2-2.3 (9H, m), 2.40 (3H, s), 3.95 (1H, m) and 4.42 (2H, q, J 7 Hz).

Sources & evidence

ORD record
ord-54ad926c1eea4f58aeab1e972aaa129d
Source dataset
uspto-grants-1989_03
Patent number
US04816452

Reaction notes

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