HRID1194900

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID139060

Bicyclo(2.2.2)octane, 1-bromo-

C8H13Br

$结构：CCOC(=O)/C(=N\O)C(C)=O$

HCID178472876

未命名化合物

PRODUCTS

生成物

$结构：CCOC(=O)/C(=N\OC12CCC(CC1)CC2)C(C)=O$

HCID14864974

未命名化合物

收率 22.6%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID76223

Methanesulfonic acid, trifluoro-, silver(1+) salt

CAgF3O3S

PROCEDURE

实验过程

1-Bromobicyclo[2.2.2]octane (4.6 g, 24.3 mmol), ethyl (Z)-2-hydroxyimino-3-oxobutyrate (3.78 g, 24.3 mmol) and silver trifluoromethanesulphonate (6.32 g, 24.6 mmol) were reacted under similar conditions to that described in Example 31a to give the title compound (1.47 g, 22%); νmax (CH2Cl2) 2950, 2925, 2860, 1735, 1685, 1370 and 1325 cm-1 ; δH (60 MHz, CDCl3) 1.30 (3H, t, J ca 7 Hz), 1.64 (S) and 1.75 (s) (together 13H), 2.36 (3H, s), and 4.30 (2H, q); [Ammonia CI mass spectrum Found MH+ (288)].