Potassium Bromide → HCID 88627693, compound

HRID 1194919Notes

Reaction equation

[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:13]/[O:14][CH:15]2[CH2:24][CH2:23][CH:22]3[CH:17]([CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:16]2)/[C:8]([O:10]CC)=[O:9])[N:6]=1.[K+].[Br-]>>[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:13]/[O:14][CH:15]2[CH2:24][CH2:23][CH:22]3[CH:17]([CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:16]2)/[C:8]([OH:10])=[O:9])[N:6]=1

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 88627630HCID 88627630, compound

Product 1

HCID 88627693HCID 88627693, compoundYield 79.2%

Procedure

Ethyl 2-(2-aminothiazol-4-yl)-(Z)-2-(decahydronaphth-2-yloxyimino)acetate (0.48 g) was hydrolysed as described in Example 4e to give the title compound (0.35 g), νmax (KBr) 3118, 2920, 1625, and 1013 cm-1, δH [(CD3)2SO]0.8-2.1 (16H, m), 4.06 (1H, m), 6.82 (1H, s), and 7.26 (3H, br s).

Sources & evidence

ORD record: ord-20c39a9e19644adaa27f8696073465cd
Source dataset: uspto-grants-1989_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04816452

Reaction notes

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