HRID1194931

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：O=C(OC(c1ccccc1)c1ccccc1)/C(=N\OC1(C(=O)OCc2ccc([N+](=O)[O-])cc2)CCCCC1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1$

HCID21248854

未命名化合物

PRODUCTS

生成物

结构：Nc1nc(/C(=N/OC2(C(=O)OCc3ccc([N+](=O)[O-])cc3)CCCCC2)C(=O)O)cs1

HCID21248864

未命名化合物

收率 85.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID284

Formic acid

CH2O2

PROCEDURE

实验过程

Benzhydryl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(1-(4-nitrobenzyl)oxycarbonylcyclohexyloxyimino)acetate (1.3 g) was treated with aqueous formic acid as described in Example 23d to give the title compound (0.58 g, 85%) as a white solid. m.p. 184°-185° C., [Found: C: 50.94; H: 4.56; N: 12.48. C19H20N4O7S requires C: 50.89; H: 4.50; N: 12.49%] νmax (KBr) 3358, 2939, 1735, 1608, 1515, and 1346 cm-1, δH (CDCl3) 1.28 (1H, m), 1.52 (5H, m), 1.78 (2H, m), 2.01 (2H, m), 5.34 (2H, s), 6.80 (1H, s), 7.31 (2H, br s), 7.63 (2H, d), and 8.13 (2H, d).