Hydrochloric Acid → HCID 12330040, compound

HRID 1195028Notes

Reaction equation

HRID 1195028 reaction equation
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][C:18]([O:20][CH3:21])=[O:19])=[CH:16][C:3]1=2.[BH4-].[Na+].Cl.[CH3:25]O>>[CH3:25][O:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][C:18]([O:20][CH3:21])=[O:19])=[CH:16][C:3]1=2

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 4311764Sodium borohydrideHCID 10333952Methyl (11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate

Product 1

HCID 12330040HCID 12330040, compound

Procedure

A mixture of 5.64 g. of methyl 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetate, 0.4 g. of sodium borohydride and 250 ml. of methanol is stirred at 0°-2° for four hours. The reaction product is treated with 1N hydrochloric acid and extracted with chloroform, and the chloroform extracts are washed with saturated sodium bicarbonate solution and dried with sodium sulfate. The chloroform is evaporated to leave methyl 6,11-dihydro-11-methoxydibenz[b,e]oxepin-2-acetate as an oil;

Workup

  1. additionA mixture of 5.64 g
  2. extractionextracted with chloroform
  3. washthe chloroform extracts are washed with saturated sodium bicarbonate solution
  4. dry with materialdried with sodium sulfate
  5. customThe chloroform is evaporated

Sources & evidence

ORD record
ord-d99ff9aefc3643ea8a29f6c960075a94
Source dataset
uspto-grants-1989_03
Patent number
US04816591

Reaction notes

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